Pantoprazolum [Inn-Latin]
Brand names,
Pantoprazolum [Inn-Latin]
Analogs
Pantoprazolum [Inn-Latin]
Brand Names Mixture
Pantoprazolum [Inn-Latin]
Chemical_Formula
C16H15F2N3O4S
Pantoprazolum [Inn-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/protonix.htm
Pantoprazolum [Inn-Latin]
fda sheet
Pantoprazolum [Inn-Latin]
msds (material safety sheet)
Pantoprazolum [Inn-Latin]
Synthesis Reference
No information avaliable
Pantoprazolum [Inn-Latin]
Molecular Weight
383.371 g/mol
Pantoprazolum [Inn-Latin]
Melting Point
Because of gradual degradation of pantoprazole sodium during heating, the melting point cannot be determined.
Pantoprazolum [Inn-Latin]
H2O Solubility
Freely soluble in water.
Pantoprazolum [Inn-Latin]
State
Solid
Pantoprazolum [Inn-Latin]
LogP
1.268
Pantoprazolum [Inn-Latin]
Dosage Forms
Tablet (enteric-coated)
Pantoprazolum [Inn-Latin]
Indication
Short-term (up to 16 weeks) treatment of erosive esophagitis.
Pantoprazolum [Inn-Latin]
Pharmacology
Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.
Pantoprazolum [Inn-Latin]
Absorption
Pantoprazole is well absorbed; it undergoes little first-pass metabolism resulting in an absolute bioavailability of approximately 77%.
Pantoprazolum [Inn-Latin]
side effects and Toxicity
No information avaliable
Pantoprazolum [Inn-Latin]
Patient Information
Patients should be cautioned that PROTONIX Delayed-Release Tablets should not be split, crushed or chewed. The
tablets should be swallowed whole, with or without food in the stomach. Concomitant administration of antacids does
not affect the absorption of pantoprazole.
Pantoprazolum [Inn-Latin]
Organisms Affected
Humans and other mammals